Application

Biology of
Asthma and Allergic Disease

The primary
objective of this assignment is to introduce you to the major biological
concepts that are associated with asthma and allergic disease. This Application
focuses on the role of various biological processes involved in the chronic
illnesses of asthma and allergy. Complete the following steps.

1.Read the
article by Dale Umetsu and Rosemarie DeKruyff, “The Regulation of Allergy
and Asthma.”?Umetsu, D. T., & DeKruyff, R. H. (2006). The regulation
of allergy and asthma. Immunological Reviews, 212(1), 238–255. Retrieved from
the Walden Library Academic Search Premier database. (AN 21667826)

2.Read
Chapter 10, “The Respiratory System: Exchange of Gases” in the course
text, Human Biology: Concepts and Current Issues.

3.Read a
selection of the review articles presented below to gain a better or deeper
understanding of the topic and help you choose a focus area. For your
Application Assignment you must also find at least three primary research articles
in your area of interest. You may use the review articles in your Application
paper, but primary research is required for your research section. Using less
than three primary research articles will result in a deduction of points.

In the first application, you were given some
focus areas. This time, you will do your own research to choose a biological
focus; a specific area that interests you. Examples may include the
“hygiene hypothesis,” windows of exposure, nutrition and gastrointestinal
flora, helminth infections, Tregs, and NKT cells. Read the appropriate optional
articles, and then locate additional review and primary research articles on
your area of interest.

?Devereux,
G. (2006). The increase in the prevalence of asthma and allergy: Food for
thought. Nature Reviews Immunology, 6(11), 869–< /font>874. Retrieved
from the Walden Library Academic Search Premier database. (AN 22848496)

?Tantisira,
K. G., & Weiss, S. T. (2006). The pharmacogenetics of asthma therapy.
Current Drug Targets, 7(12), 1697–1708. Retrieved from the Walden Library
Academic Search Premier database. (AN 23278588)

?Umetsu, D.
T., Meyer, E. H., & DeKruyff, R. H. (2007). Natural killer T cells regulate
the development of asthma. International Reviews of Immunology, 26(1/2),
121–< /font>140. Retrieved from the Walden Library Academic Search
Premier database. (AN 24515668)

?Wohlleben,
G., & Erb, K. J. (2006). Immune stimulatory strategies for the prevention
and treatment of asthma. Current Pharmaceutical Design, 12(25), 3281–? < /font>3292. Retrieved from the Walden
Library Academic Search Premier database. (AN 22139036)

?Yeatts,
K., Sly, P., Shore, S., Weiss, S., Martinez, F., & Geller, A. et al.
(2006). A brief targeted review of susceptibility factors, environmental exposures,
asthma incidence, and recommendations for future asthma incidence research.
Environmental Health Perspectives, 114(4), 634–< /font>640. Retrieved
from the Walden Library Academic Search Premier database. (AN 20814567)

4.Write a
five page (body; double-spaced) review of the topic from a public health
biology perspective. In your review, include the following:

i.Explain the biological basis of asthma and
allergic disease, including an introduction to your chosen focus area;

ii.Discuss
some of the recent (within five years) and current research on the biological
focus area you chose, including study aim, methods, and results of the studies
you discuss;

iii.Explain
the value and application of the above research findings to public health,
citing the studies as needed, and providing some examples of how this
information is or can be used in public health policy, programs, and practice.

Your paper
must provide APA-formatted references for all resources used and adhere to APA
style and format. APA style headers will be expected for the three subsections
of biological basis, research, and public health application. Use subheaders as
needed. A title page and a reference page is required. An abstract is optional.
Use your APA manual, or get help from the Writing Center if you need it.

What are the major causes of disease and death in the 21st century (e.g., chronic illnesses, communicable diseases, etc.) that continue to affect U.S. citizens in spite of the achievements in public health in the past century? What have been some of the strategies implemented to combat these illnesses on the local and national levels? Have they been successful? Include reference citations where appropriate.

What were the major causes of U.S. mortality in the last 100 years, and what public health measures most contributed to improvements in the health of the nation? Include at least two source citations from the readings and/or additional sources to support your answer

What are the major causes of disease and death in the 21st century (e.g., chronic illnesses, communicable diseases, etc.) that continue to affect U.S. citizens in spite of the achievements in public health in the past century? What have been some of the strategies implemented to combat these illnesses on the local and national levels? Have they been successful? Include reference citations where appropriate.

What were the major causes of U.S. mortality in the last 100 years, and what public health measures most contributed to improvements in the health of the nation? Include at least two source citations from the readings and/or additional sources to support your answer