Primary manuscript analysis assignment: each GRADUATE student will be required to select a primary article studying a signal transduction pathway from a top-tier journal and provide an in-depth analysis of the article. The analysis must include the following components:
1. The complete article reference (Authors, Journal, Volume, Page numbers)
2. A two paragraph description providing the issue being addressed in the article, why it is an important topic, what is generally known about the topic to date (include 4-5 key references), and what question(s) the authors hoped to answer.
3. A list of each technique used  in the article that includes technique name, general purpose of the technique, theory behind the technique, and what the authors found using the technique.
Also include a list of controls used for each experiment and for what each is controlling.
4. A list of conclusions made by the authors from each figure.
5. The overall conclusion of the authors.
5. A critique  of the article: Which experiments were believable and which were suspect? Would better controls be more appropriate?  Doe the authors draw conclusions that are not justified? Would include other experiments to make the data set better? 

Note: l attached the primary article and you choose another 4 or 5 articles from top-tier journal. Also, make sure to include charts

Final Project Part II
Part II Overview
For this part of the final project, you will be given a scenario in which you are asked to illustrate your financial computation and analysis skills.
This part of the assessment addresses the following course outcomes:
? Compute financial ratios, time value, variables, and returns using industry standard tools for optimizing financial success
? Analyze corporate financial data for multiple companies in evaluating past and future financial performances
Part II Prompt
For this section of your employment exam, you will select two companies. The first company needs to come from your TDAU think or swim portfolio. The second
needs to be a competitor of the first company from the same industry. You will be responsible for collecting, synthesizing, and making decisions regarding both
companies. After evaluating these companies’� financial data, you will then decide which company�s stock is the better investment.
This section of your employment examination must be submitted in two parts. Part A will contain the workbooks that house all of your quantitative data and
formulas, along with any of the information that is relevant for your chosen companies. Part B will contain your answers to the questions asked below,
composed in a cohesive manner. If you are referring to data that is found within the workbooks in Part A, be sure to include a citation�, for example, �rate of
return is 3.570 USD (E64, WB2),� where E64 is the cell that the calculation took place in and WB2 is designating �workbook 2.� This ensures that your instructor
can quickly and accurately check data entry, formula use, and financial calculations.
Your submission must address the following critical elements:
I. Preparing the Workbooks
A. Download the annual income statements, balance sheets, and cash flow statements for the last three completed fiscal years for your chosen
companies. This information must be included in your final submission.
B. Prepare a worksheet for each of the companies to display their financial data for the last three fiscal years. Ensure your data is accurate and
organized. Include these worksheets as a workbook in your final submission.
C. Find historical stock prices for both companies and add this information to the respective spreadsheets. Consider the appropriate date range
you should use.
II. Three-Year Returns
A. What is the three-year return on the stock price of the first company (Company A)? How is the stock performing? Ensure that you use the
appropriate formula in your spreadsheets to calculate the three-year return on the given company�s stock price.
B. What is the three-year return on the stock price of the second company (Company B)? How is this stock performing? Ensure that you use the
appropriate formula in your spreadsheets to calculate the three-year return on your chosen company�s stock price.
C. How do these two stocks compare in terms of three-year returns? What does this indicate about these two companies?
III. Financial Calculations
A. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the price-to-earnings ratio for the last three fiscal
years of the given and your chosen companies. Be sure that you are entering and using the correct formula.
B. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the debt-to-equity ratios for the last three fiscal years
of the given and your chosen companies. Be sure that you are entering and using the correct formula.
C. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the return-on-equity ratios for the last three fiscal
years of the given and your chosen companies. Be sure that you are entering and using the correct formula.
D. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the earnings per share for the last three fiscal years of
the given and your chosen companies. Be sure that you are entering and using the correct formula.
E. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the profit margins for the last three fiscal years of the
given and your chosen companies. Be sure that you are entering and using the correct formula.
F. Using the appropriate spreadsheets, which are to be included in the workbooks, calculate the free cash flows for the last three fiscal years of the
given and your chosen companies. Be sure that you are entering and using the correct formula.
IV. Industry Averages
A. Obtain current industry averages of three of the financial calculations above for both companies and add this information to your spreadsheet
for comparison. Ensure the accuracy and organization of your data.
B. In this context, how is each company�s financial health? How do these two companies compare to one another? Consider the appropriate date
range you should use.
V. Performance Over Time
A. Analyze the performance of the Company A over time. What financial strengths and weaknesses does this company have? Consider addressing
the free cash flows and ratios you calculated earlier.
B. Analyze the performance of your Company B over time. What financial strengths and weaknesses does this company have? Consider addressing
the free cash flows and ratios you calculated earlier.
C. Analyze how the data differ between these two companies. Why do you think this is? Consider addressing the free cash flows and ratios you
calculated earlier.
VI. Investment
A. Are the companies considered growth or value companies? Why?
B. Which company�s stock is the better investment? Consider supporting your answer with data.

Sample Solution

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