Which of the following techniques detect genome-wide variation?

Which of the following techniques detect genome-wide variation? Allele specific PCR and capillary electrophoresis, MLPA O FISH, PCR and restriction digestion, Southern blot analysis Sanger sequencing, karyotype, FISH OaCGH, SNP array, exome/genome sequencing, karyotyp

Which of the following techniques detect copy number changes? OaCGH, Southern blot analysis, quantitative PCR, FISH, karyotype O Sanger sequencing, PCR and restriction digestion, O PCR and capillary electrophoresis O Allele specific PCR