What were the ethical principles violated in the interaction between patients and doctors?

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After you watch the documentary The Deadly Deception presenting the infamous Tuskegee Study, please respond to the questions below.

https://www.youtube.com/watch?v=FZquBH0CH24

watch these two videos and answer the question 3-4 sentances for each question

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1. What were the ethical principles violated in the interaction between patients and doctors?

2. What other parties had interests in this case and what were these interests?

3. What were the arguments used by the defenders of the study to justify its execution?

4. What was wrong with these arguments?

5. How is this experiment similar to the experiments performed by Nazi doctors?

6. What can we do to make sure such experiments are not carried out ever again?