The patho-physiology of Cystic Fibrosis

Case Study: You are a nurse practitioner working in the urology department. You are scheduled to see Mr. Pogue, a 27-year-old active-duty member of the military who was referred for the evaluation of infertility. When the Mr. Pogue and his wife were seen in the OB/GYN clinic a month ago, a screening semen analysis demonstrated azospermia (lack of sperm). Mr. Pogue says that in general he is well except for a long history of increased frequency of upper respiratory tract infections. A variant of cystic fibrosis (CF) is associated with respiratory symptoms and infertility. Answer the following:

Describe briefly in one paragraph what is the pathophysiology of Cystic Fibrosis?

Explain the signs and symptoms of Cystic Fibrosis and provide rationale.

Evaluate the risks for the inheritance of Cystic Fibrosis.

Sample Solution

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