Setting A Strong Influence

Setting can have a great influence on the characters and plot of a story. For example, in the TV show Hawaii 5-0, the island acts as a limiter, a finite area in which plot events can take place. And the island also influences how the characters behave.

Post an example of a TV show or movie or book in which the setting is a strong influence. Explain how the story (plot and/or characters) would have to be very differentor perhaps could not be told at allif the setting were changed.