Part One: Stress and Immune Dysfunction Related to Diseases
When it comes to stress and immune system responses, you can have too much of a good thing. It is true that the stress involved in exercising or achieving goals can be great for your mind and body. Even the stress that propels you to escape danger can ultimately save your life. Yet, ongoing stress is harmful to the body. In previous weeks you explored the dangers associated with prolonged stress. You also examined the relationships among stress, inflammation, and depression. As a health psychology professional educating populations on the prevention and treatment of disease, it is necessary to consider the relationships among stress, inflammation, and depression in the context of specific chronic diseases.
For this Assignment, review this week’s Learning Resources. Select a disease for your Final Project from the following list:
Cancer
HIV
Type I Diabetes
Type II Diabetes
Fibromyalgia
Graves Diseases
Asthma
Colitis
Rheumatoid Arthritis
Cardio Vascular Disease
Then, search the Walden Library for at least three articles regarding the possible relationship between depression and the disease you selected as well as the immune dysfunction or imbalance for that disease. Finally, consider how stress influences the immunity of the disease you selected.
Note: It is recommended that you review the book chapters authored by Kendall-Tackett and the articles authored by O’Malley, Wilson, Dantzer, Gill, and Leonard from Weeks 3 and 4 while preparing your Assignment.
The Assignment (6–8 pages, not including the title, abstract or reference pages):
Submit an APA-formatted essay that includes the following:
A description of the disease you selected
An explanation of the possible relationship between depression and the disease you selected
An explanation of the immune dysfunction or imbalance for that disease
An explanation of influences of stress on the immune response of the disease you selected
Support Part One of your Final Project assignment with specific references to all resources used in its preparation. Use at least three articles to support Part One. You are to provide a reference list for all resources, including those in the Learning Resources for this course.
Readings
Ader, R. (2001). Psychoneuroimmunology. Current Directions in Psychological Science, 10(3), 94–98.Retrieved from the Walden Library databases.
Bovbjerg, D. H. (2003). Conditioning, cancer, and immune regulation. Brain, Behavior, and Immunity, 17(1), S58–S61.Retrieved from the Walden Library databases.
Dantzer, R. (2001). Cytokine-induced sickness behavior: Where do we stand? Brain, Behavior, and Immunity, 15(1), 7–24.Retrieved from the Walden Library databases.
Meissner, K., Bingel, U., Colloca, L., Wager, T. D., Watson, A., & Flaten, M. A. (2011). The placebo effect: Advances from different methodological approaches. The Journal of Neuroscience, 31(45), 16117–16124.Copyright 2012 by The Journal of Neuroscience: the official journal of the Society for Neuroscience. Used by permission of Society For Neuroscience via the Copyright Clearance Center.
Prasher, D. (2009). Is there evidence that environmental noise is immunotoxic? Noise & Health, 11(44), 151–155.Retrieved from the Walden Library databases.
Stewart-Williams, S. (2004). The placebo puzzle: Putting together the pieces. Health Psychology, 23(2), 198–206.Retrieved from the Walden Library databases.
Goebel, M. U., Trebst, A. E., Steiner, J., Xie, Y. F., Exton, M. S., Frede, S., …Schedlowski, M. (2002). Behavioral conditioning of immunosuppression is possible in humans. The Journal of the Federation of American Societies for Experimental Biology, 16(14), 1869–1873. Retrieved from http://www.fasebj.org/content/16/14/1869.full.pdfCopyright 2002 by The FASEB Journal. Used by permission of FEDN OF AM SOCIETIES FOR EXPERIMENTAL BIO (FASEB) via the Copyright Clearance Center.
Optional Resources
Exton, M. S., Herklotz, J., Westermann, J., & Schedlowski, M. (2001). Conditioning in the rat: An in vivo model to investigate the molecular mechanisms and clinical implications of brain-immune communication. Immunological Reviews, 184(1), 226–235.Retrieved from the Walden Library databases.
Goebel, M. U., Meykadeh, N., Kou, W., Schedlowski, M., & Hengge, U. R. (2008). Behavioral conditioning of antihistamine effects in patients with allergic rhinitis. Psychotherapy and Psychosomatics, 77(4), 227–234.Retrieved from the Walden Library databases.
Leandro, C. G., de Lima, T. M., Folador, A., Alba-Loreiro, T., do Nascimento, E., de Castro, R. M., … Curi, R. (2006). Physical training attenuates the stress-induced changes in rat t-lymphocyte function. Neuroimmunomodulation, 13(2), 105–113.Retrieved from the Walden Library databases.
Vits, S., Cesko, E., Enck, P., Hillen, U., Schadendorf, D., & Schedlowski, M. (2011). Behavioural conditioning as the mediator of placebo responses in the immune system. Philosophical Transactions of the Royal Society B, 366(1572), 1799–1807.
The Dana Foundation. (n. d.). Immune conditioning in premalignant HPV disease. Retrieved from http://www.dana.org/grants/human/detail.aspx?id=8820
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