Citrate to prevent future stone formation

What enzyme been used to regulate stone formation a patient diagnosed with kidney stone

Patient has pain in left flank and was diagnosed to have kidney stone was described citrate to prevent future stone formation, citrate is isomerized and subsequently converted into alpha keto glutarate by a regulatory enzyme in TCA cycle, which enzyme is it?
Aconitase, citrate synthase , succinyl-coA synthase, alpha ketoglutarate dehydrogenase, Isocitrate dehydrogenase

Sample Solution

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