How is cultural change analogous to biological evolution

How is cultural change analogous to biological evolution Forum Question: How is cultural change analogous to biological evolution? What important limitations are there to this analogy? In order to fully answer this question, consider issues of cultural innovation and cultural evolution. ONLY NEED TO BE 250 WORDS —————————————————————————————————————————————————————————————————————– Forum Question: During this course we will be exploring many facets of Anthropology. I think it is important to remember those early practitioners of the field who really are responsible for guiding and shaping anthropology into the science it is today. A very influential anthropologist, Marvin Harris, focused his research on trying to understand why societies responded to issues the way they did. His work culminated in the theory of cultural materialism, which notes that human social life is a response to the practical problems of earthly existence. Please use your textbook or an outside source to define cultural materialism. Do you agree with this concept? Is human social life a response to outside problems and concern or are there other forces at work? What could they be?

Describe the expected result of a nonsense mutation in the gene for Mad1.

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1. The plasmid vector pBR322 has both ampicillin and tetracycline resistance determinants. How could the resistance markers of this vector be used to identify recombinant plasmid molecules in a cloning experiment?

2. A functional genomics experiment is carried out using a DNA chip to assay levels of gene expression in a species of bacteria. What types of genes would you expect to find over-expressed in cells grown in minimal medium compared to cells grown in complete medium containing all nutritional supplements?

3. a. On one line each, list all of the mutations that can result from a single base substitution in the tryptophan codon UGG.

b. Going back to the above lines, classify each of the mutations as silent, missense, or nonsense. Then justify your answer below

4. Suppose that every human gamete contains approximately 40,000 genes.
a. If the forward mutation rate is 1 x 10-5 new mutations per gene per generation, what is the average number of new mutations per gamete per generation? Show your work.

b. What is the average number of new mutations per gamete per generation if the forward mutation rate is 1×10-4? Show your work.

5. Describe the expected result of a nonsense mutation in the gene for Mad1. Be specific and justify your answer.

6. The following gel diagram shows the pattern of bands observed in a Southern blot for three tightly linked SSR molecular markers in and flanking the p16 gene in a family in which familial melanoma is found. Mutations in p16 are known to be associated with this cancer. Shown are an affected father, an unaffected mother, and an affected son. The bands A1 and A2 are for one SSR, with alleles A1 and A2, and the bands B1 and B2 are for another SSR, with the alleles B1 and B2. The p16+ and p16? bands are for the SSR for p16, where the wild type p16+ allele yields a band 1.0kb larger than the p16?? mutant.

Please choose one of the topics below for your research proposal. Ensure that all databases, publications, professional/trade organizations, internet searches, etc. that you consulted are properly referenced.

MGT 600

Deliverable Length: 2 – 3 pages in MS Word

A request-for-proposal (RFP) has been recently sent to three consulting firms. The research contract will be awarded to the firm that has the best proposal. Your manager has requested that you spearhead the development of a response to the RFP. This is a significant contract that has the potential to get you promoted. As such, your onus is to craft the best research proposal to ensure the win for your firm.

Please choose one of the topics below for your research proposal. Ensure that all databases, publications, professional/trade organizations, internet searches, etc. that you consulted are properly referenced.

  • Effect of Family Income on a Student’s S.A.T. Score
  • Salary Discrimination in the National Basketball Association
  • The Effect of Executive Compensation on Corporate Performance
  • The Risk Factors of Heart Attack
  • Factors Affecting Freshman Admissions to AIU
  • The Effects of Nutritional Labels and Advertisements on the Daily Consumption of Fat
  • An Analysis of the Increase in the Number of Single Parent Families
  • Health Care of America
  • Demand for Electric Vehicles: A Second Chance for the 21st Century
  • The Effects of Gender, Income, Race on Salary Distribution
  • The Impact of Credit Card Incentive Packages on Consumer Borrowing
  • The Effects of Rap Music on Violent Behavior Among African American Teenagers

AGAIN — Be sure to include all references/information sources.

RUBRIC:

Content/Research13
Communication of Ideas13
Critical Thinking12
Grammar/APA Style12

What concerns do you have about PNI”s supply chain management practices?

Peak Nutrition, Inc.

Peak Nutrition, Inc. (PNI) offers a line of premium sports recovery drinks. Its drinks are made from all-natural fruit juices that are supplemented with protein, creatine, vitamins, and minerals. Each flavor is offered in both a 12-ounce and 20-ounce bottle. Eighty percent of PNI”s sales are to two national health food chains, and the remaining 20 percent are to independent health food stores and online retailers.

PNI has a single production and bottling line, which has sufficient capacity to meet its current demand. Setting up the production line to produce a particular flavor requires an entire eight-hour shift. Most of the setup time is related to flushing out the equipment in order to not contaminate the new flavor to be produced with the flavor that was last produced. Given the long setup times, the production and bottling lines are dedicated to producing a single flavor for an entire week. The typical production schedule involves setting up the line on Monday, producing 12-ounce bottles on Tuesday and Wednesday, and producing 20-ounce bottles on Thursday and Friday. The plastic bottles and labels are purchased from outside suppliers. There is a one-week lead time for both the bottles and labels. PNI maintains a four-week inventory of plastic bottles and orders labels three weeks before they are needed. Changing over the bottling line from 12-ounce to 20-ounce bottles requires about an hour and a half, which also includes changing the labels.

Since each flavor is produced every six weeks, PNI historically produced an eight-week supply for each flavor to provide a safety net in the event demand exceeded its forecasts. Despite having an extra two weeks of inventory, PNI often experienced stockouts. Given the problem with stockouts, PNI recently acquired additional warehouse space and now plans to produce ten weeks of demand during each production run. It is expected that producing a ten-week supply may result in the need for a small amount of overtime in some weeks.

PNI has limited communication with its customers, primarily consisting of the purchase orders it receives from its customers and the invoices and products it sends to them. PNI”s goal is to meet all orders from its inventory. In this way, it is able to provide its customers with a one-week lead time. When the inventory level is insufficient to meet the quantity ordered, lead times increase to an average of two to three weeks, depending on how soon the product is next scheduled for production. Once last year PNI was stocked out of a flavor for almost four weeks.

At the end of each quarter, PNI offers its customers discounts for orders above certain order quantity thresholds. The purpose of the discounts is to provide retailers with an incentive to put the sports drinks on sale and help boost quarterly sales. As a result of these incentives, PNI”s sales tend to be five to ten times higher in the last two weeks of the quarter compared to other times. In anticipation of the increase in sales, PNI builds up its inventory. However, while on average it has plenty of inventory across all flavors, it often experiences mismatches in its available supply and demand for specific flavors. In other words, it often finds that it has too much inventory of some flavors and too little of other flavors.

Questions

  1. What concerns do you have about PNI”s supply chain management practices?
  2. What would you recommend PNI do to address your concerns?
  3. Do you have any concerns about the way PNI determines its level of safety stock?
  4. Should PNI focus on enhancing the efficiency or responsiveness of its supply chain? Why?