A nurse practitioner is teaching her colleagues about the role of cytokines in a variety of pathologies. Which of the following teaching points best captures an aspect of the functions and nature of cytokines?

.A nurse practitioner is teaching her colleagues about the role of cytokines in a variety of pathologies. Which of the following teaching points best captures an aspect of the functions and nature of cytokines?

(Points : 0.4)
A particular cytokine can have varied effects on different systems a fact that limits their therapeutic use.
Cytokine production is constant over time but effects are noted when serum levels cross a particular threshold.
Most cytokines are produced by granular leukocytes and different cells are capable of producing the same cytokine.
Cytokine actions are self-limiting in that activation of one precludes activation of other cytokines with similar actions.

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