F.G., a 56-year-old woman, is admitted for a cervical laminectomy. She has a history of chronic…
F.G., a 56-year-old woman, is admitted for a cervical laminectomy. She has a history of chronic kidney disease (CrCl 20 mL/minute) and arrhythmias that are treated with procainamide. Her admission laboratory values are as follows: SCr, 4.4 mg/dL BUN, 66 mg/dL Hematocrit, 34% Hemoglobin, 12.6 g/dL After surgery, she complains of severe pain and is treated with meperidine 50 to 100 mg intramuscularly every 3 to 4 hours. Three days postoperatively, F.G. experiences a generalized tonic-clonic seizure. She has no history of seizures. What might be responsible for this sudden event?
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