Variations in Drug Response

Using the knowledge you gained from the readings, evaluate how a typical drug, when orally administered, may be handled differently by these two patients:Ms. Jones is a 30-year-old female personal trainer that is 5’ 4” tall weighing 110lbs. She regularly drinks socially and sometimes more than a bit when she meets with her bi-weekly book club.Mr. Smith is a 65-year-old software tester who is 6’ tall and weighs 235lbs. He drinks only occasionally.Assume no other significant medical history or issues with either patient. In your analysis, compare how the two patients will metabolize the drug considering weight, gender, distribution of body water and body fat, age, metabolic state, and alcohol use. Explain how these factors impact the pharmacokinetics of the drug (half-life, dosage, route of administration, and elimination of the drug). Evaluate the impact on the risk-benefits analysis of the use of this drug.

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Assignment 1As you prepare to write this discussion, take a few moments to do the following:Review the Modeled Discussion.Read any required and recommended reading materials for this week, especially Chapters 3 and 10 in your text.Then, watch the following movie clips, paying special attention to the cinematic elements under the discussion.Editing – visual transitions between shots that work to move the story forwardWatch the following clips. Each demonstrates the effective use of editing.The Baptism Murders – The Godfather (8/9) Movie Clip (1972) HDA Beautiful Mind (4/11) Movie Clip – Nash Cracks the Code (2011) HDTranscriptThe Shower – Psycho (5/12) Movie Clip (1960) HDTranscriptCinematography – camera angles, types of shots, framing, and color all working to set a particular moodWatch the following clips. Each demonstrates the effective use of cinematography.The Long Take: GoodfellasTranscriptManhattan – The Bridge SceneTranscriptMiriam’s Last Breath – Strangers on a Train (4/10) Movie Clip (1951)TranscriptLighting – light and shadow used to affect the mood, the way we view characters, and set the overall tone of the filmWatch the following clips. Each demonstrates the effective use of lighting.Jurassic Park (10/10) Movie Clip – Raptors in the Kitchen (1993) HDTranscriptLost in Translation (7/10) Movie Clip – Bob and Charlotte Meet (2003) HDThe Stuff that Dreams Are Made of – The Maltese Falcon (10/10) movie clip (1941) HDTranscriptWrite (due Thurday)Analyze each of these aesthetic choices by following the instructions below. Your initial post should be at least 300 words in length. Support your claims with examples from the required material(s) and/or other scholarly sources, and properly cite any references.Choose one of the clips from the “Editing” section and analyze the use of editing in one short paragraph. In your analysis, describe the transitions between specific shots and the overall effect this has on the scene.Choose one of the clips from the “Cinematography” section and analyze the use of cinematography in one short paragraph. In your analysis, describe the way specific shots are composed, paying particular attention to the camera angles, types of shots, framing, color, and the overall effect this has on the scene.Choose one of the clips from the “Lighting” section and analyze the use of lighting in one short paragraph. In your analysis, describe the way the light looks in specific shots, how it affects the mood and the way we view characters, and how it sets the overall tone of the film.Assignment 2As you prepare to write this discussion, take a few moments to do the following:Read any required and recommended reading materials for this week, especially Chapter 3 from the text.Select a full-length film from the AFI 10: Top 10 list.Our textbook sets up a distinction between story and plot, stating that story is what happens in a movie, and plot is how it happens. The distinction may seem minor; however, throughout this course, we will be scrutinizing the various aesthetic choices and cinematic techniques that work together to create meaning in any movie. With that in mind, we can see that how a film presents action can be very important.In at least 300 words, describe the relationship of story to plot in your chosen film. Be sure to:Identify the title, writer, director, major actors, and the year.Summarize the story and plot of your chosen movie.Discuss whether your film is presented chronologically or non-linearly. In your discussion, address the following:How did this aesthetic choice contribute to the general effect on the audience?How are elements like character development or foreshadowing impacted by the choice of storytelling methods?If the film had followed a different presentation style, how would the general effect on the audience have been different?You must use at least two outside sources, in any combination of embedded video clips, still photos, or scholarly sources. All sources should be documented in APA style.

Discuss the ways how human resource management controls social networking.

Compose a 2000 words assignment on the ways how human resource management controls social networking. Needs to be plagiarism free! Social networking is a useful tool, which can be used by companies as a way of communication between supervisors and subordinates. Moreover, social networking can form alliances and workers can help each other in their work by sharing information among them.

Due to the traditional hierarchy, the flow of information among different departments and level of managements were difficult and time-consuming and resulted to be the cause of delayed work and decisions. Social networking websites proved to be proficient in this regard as it quickly delivers the message between managers and the employees and the managers can make decisions instantly, without wastage of time. According to Swartz, a corporate social network make the duration of time shorter because these social webs convey the message in the minimum time possible. Social networking indirectly decreases the completion time of work because it decreases the time that traditional ways take to make contact between the managers and the employees (Baker et al. 2011).

Along with the benefits of quick communication, social networking websites provide the opportunity to share the information needed between two employees, companies and subordinates. Organizations find new businesses, joint ventures, and alliances through social networks and it allows companies to look for attractive marketing strategies and techniques.

Damien Cummings, who is the online and social media director of Dell, says that Dell in involving social networking in everything that its employees do because it the best way to contact with the employees and get their regular feedback regarding the company’s policies and it is the source of getting innovative ideas, which can be implemented in the future (Selvaretnam 2011).

The things that make social networking beneficial also do the damage, so it is a matter of concern for the HRM and senior executives when the employees socialize during working hours.

Health effects of illegal substance use

Explore the health effects of illegal substance use with legal substances. Do all substances generate health problems? Why or why not?