Write 7 pages with APA style on Identifying Outliers in a Large Biological Data Base.

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Write 7 pages with APA style on Identifying Outliers in a Large Biological Data Base. The Pro-Kmeans Algorithm involves partitioning that is randomly performed on a set of data which are then put into clusters and then later makes use of the Smith-Waterman algorithm in an effort to come up with a comparison of each protein cluster as well as computing each protein’s SumScores. The sequence in the respective cluster which happens to have the most SumScores is normally regarded as the cluster’s centroid (Tatusov, 2003). The Smith-Waterman algorithm is applied at this stage to compare the respective protein in the set of data provided with the found centroids and also used in the assigning of objects to the cluster that is nearest to the maximum score and is similar to the identified object. This algorithm repeats the above process many times so as to come up with the maximum function. In this kind of algorithm, the number of clusters forms the input parameter with the output being the most suitable partition in the entire set of data used (Sasson and Linial, 2002).

Pro-LEADER algorithm

Pro-LEADER algorithm involves the selection of the first sequence forming the set of data making it the first leader and goes ahead to make use of the Smith-Waterman algorithm to calculate the similarity score of every sequence represented in the data set with all leaders. This algorithm operates in such a way that it identifies the nearest leader to every sequence and goes further to compare the scores with a threshold that is normally pre-fixed. If the score of the nearest leader happens to be larger than the threshold used, then the sequence will be taken as the new leader. If this does not happen then the sequence has to be assigned to the cluster which is defined by the leader (Herger and Holm, 2001). This makes pro-LEADER an incremental algorithm where each of the clusters has to be represented by an identified leader. These clusters are reached by the use of threshold values that are most suitable. The aim of this algorithm is to have the function maximized. Its input parameter happens to be the threshold similarity score considering an object as being a new leader while its output is the best partition returns of the training data set as well as the number of the leaders of the clusters that have been obtained.

writing homework on Qualitative and Quantitative Problem Statements.

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Need help with my writing homework on Qualitative and Quantitative Problem Statements. Write a 750 word paper answering; Qualitative and quantitative research ments Qualitative ment of the problem- Euthanasia Euthanasia remains a controversial issue in the society. Some jurisdictions have legalized it while others have not and divergent views and regulations exist. In the Netherlands, the practice is legal even though patients and physicians do not have rights to the practice. The process of making decision into euthanasia also remains complex and requires emotional support to both patients and physicians (Dees, Vernooji-Dassen, Dekkers, Elwyn, Vissers and Weel, 2013). Different types of stakeholders also hold different opinions towards euthanasia. Experienced nurses from Poland identify familiarity with the practice and explain that a person’s philosophy in life is the most significant factor in people’s perception on euthanasia. This therefore also affects decision-making process among stakeholders to an instance towards need for euthanasia. The position is based on consideration of majority perceptions because divergent opinions exist (Brzostek, Dekkers, Zalewski, Januszewska and Gorkiewiecz, 2008). Differences in opinions on euthanasia also exist in legal and social environments. While the Netherlands has a legal environment that supports euthanasia, though under regulations, historical trends in Spain shows a shift towards illegalization of euthanasia. Experienced cases have led to regional legislations against euthanasia, in Spain, and the central government has also attempted to make the practice illegal (Simon-Lorda and Barrio-Cantalejo, 2012). Despite the possible variation in perception by legal jurisdiction, convergence of themes among societies across legal environments exists (Siu, 2010). Existing literature however fails to inter-relate these factors to perception on euthanasia for informed policies. Problem description, qualitative approach A qualitative approach involving focus groups from different countries will illustrate different perceptions of factors around the euthanasia debate in their localities. Each of the focus groups will be composed of people who have experienced euthanasia as a caregiver of a relative to a patient to whom the practice was administered. Developed information from different groups will then be incorporated to develop a model for understanding environmental factors affecting people’s perception on euthanasia. This will inform health policy makers in developing policies that are sensitive to the society’s needs over administration of euthanasia so that the policies do not contradict people’s fundamental values. Problem description, quantitative approach A survey on factors that people consider or may consider in making decisions towards administration of euthanasia will demonstrate positions on the euthanasia debate. Sampling participants from diversified populations and administering questionnaires proposed factors to the euthanasia debate would aid the study that will review frequencies of considered factors to identify their significance to the debate across sub populations. Results of the study will demonstrate people’s opinions on euthanasia and explain potential effects that legislations on the practice can offer. This will offer a basis for informed policies on administration of euthanasia. Quantitative statement of the problem- Relationship between leadership styles in nursing and outcomes in delivered care Leadership involves influence of followers towards achievement of set objectives and is important in change implementation or in transformation of operational environments. Different leadership styles exist and while situational leadership theory suggest that environments dictate leaders’ level of effectiveness (Fairholm and Fairholm, 2009), the notion that leaders are nurtured means that leadership potentials can be nurtured to effectiveness under any environment. Different leadership styles and theories exist that are applicable in nursing. While many nursing professionals seem to be inclined towards transformational leadership, other leadership styles, such as transactional leadership can offer effectiveness to leadership outcomes in nursing (Giltinane, 2013). In mental nursing environment, for instance, “transformational and distributed leadership” styles are associated with highest levels of success in care provision (Cleary, Horsfall, Deacon and Jackson, 2011, p. 632). While the findings were limited to micro conditions, a wider perspective of organizations may develop better insights into effectiveness of leadership styles. A correlation study to investigate relationship between leadership styles and effectiveness also noted a significant difference between leadership styles’ effectiveness with transformational style as the most effective followed by transactional style (Casida and Parker, 2011). Conflicting knowledge between theory and empirical results on effectiveness of leadership identifies the need for a study on relative effectiveness of leadership styles for identification of a style that offer general effectiveness despite environments. Problem description, qualitative approach Administering questionnaires on perceived effectiveness of leadership styles based on personnel and patient’s experiences with health facilities will demonstrate relative effectiveness of leadership styles. Developed information will help health care facilities to focus on recruitment and nurturing of types of leaders that can improve service delivery despite their environments. Problem description, quantitative approach The study will involve survey on facilities with different predominant leadership styles and use questionnaires to rank patients’ level of utility. Data analysis of effectiveness across leadership style will identify the most effective leadership style that can then be nurtured for improved leadership. The results are important to care facilities, care personnel, and patients because of their interest in quality of offered services. References Brzostek, T., Dekkers, W., Zalewski, Z., Januszewska, A. and Gorkiewiecz, M. (2008). Perception of palliative care and euthanasia among recently graduated and experienced nurses. Nursing Research 15(6), 761-777. Casida, J. and Parker, J. (2011). Staff nurse perceptions of nurse manager leadership styles and outcomes. Journal of Nursing Management 19(4), 478-486. Cleary, M., Horsfall, J., Deacon, M. and Jackson, D. (2011). Leadership and mental health nursing. Issues in the Mental Health Nursing 32(10), 632-639. Dees, M., Vernooji-Dassen, M., Dekkers, W., Elwyn, G., Vissers, K. and Weel, C. (2013). Perspectives of decision making in request for euthanasia: A qualitative research among patients, relatives, and treating patients in the Netherlands. Palliative Medicine 27(1), 27-37. Fairholm, M. and Fairholm, G. (2009). Understanding leadership perspectives: Theoritical and practical approaches. New York, NY: Springer. Giltinane, L. (2013). Leadership styles and theories. Nursing Standard 27(41), 35-39. Simon-Lorda, P. and Barrio-Cantalejo, I. (2012). End of life healthcare decisions, ethics and law: The debate in Spain. European Journal of Health Law 19(4), 355-365. Siu, W. (2010). Communities of interpretation: Euthanasia and assisted suicide debate. Critical Public Health 20(2), 169-199.

. past, present, and future paper

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I need some assistance with these assignment. past, present, and future paper Thank you in advance for the help! In general, my major motive behind learning of this particular course of drug abuse was to develop my career as a licensed substance abuse counselor and to serve community to promote healthy living habits among the people. I feel that learning is extremely important and must be continued in order to keep our skill sharp and inculcate creativity and innovation in ourselves.

Before involving in pursing course in substance abuse, my professional competencies regarding various skills such as written and oral communication, problem solving, and cooperation with the other members were moderate. Notably, I had moderate communication skills both in written as well as oral forms. In my professional life I used to involve in evaluating technical data and apply my logical and analytical problem skills in resolving work related issues. At the same time, I enjoyed taking challenges, I believed that challenges encountered in life not only test our level of competency but it also prepares me to deal with challenges that might emanate in later life. Moreover, I had fair competency with respect to the information retrieval and utilization, I often used to read of books and journals on diverse subjects that had offered me with valuable knowledge regarding information retrieval and utilization. I firmly believe that goal setting is a crucial part of my career as well as personnel development planning. Considering my strengths and weaknesses my career goal is to become a license substance abuse counselor so that I can help the drug abuse victims and their family overcomes their sufferings. I always viewed drug abuse as one of the major problems faced by the societies across the world.

Thus, it made me motivated to opt for the course and develop career that would not only benefit me but also the community.

Write 3 pages thesis on the topic annotated bibliography on the use of nuclear weapons during wwii.

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Write 3 pages thesis on the topic annotated bibliography on the use of nuclear weapons during wwii. Most of primary sources date back to the time when historical events happened. During world war two in 1945, the United States of America attacked Japan with several nuclear bombs. These bombs carry the names ‘little boy’ and ‘fat man’. Primary sources on the nuclear weapons reveal a lot of information on the effects of the bombs. Laurence, William. “NAGASAKI WAS THE CLIMAX OF THE NEW MEXICO TEST,” LIFE Vol.19 (13) (1945). 30-31. The ‘LIFE’ magazine acts as a good primary source sine it was one of the magazines reporting on the happenings of the world war in 1945. The September 24, 1945 issue had a cover photo of military men in war. This photo gave the reader an insight on the then ongoing war. That was the second war that brought about the nuclear weapons. Laurence William authored the article, “NAGASAKI WAS THE CLIMAX OF THE NEW MEXICO TEST”. The author had the mandate of making official reporting on all proceedings of the trials and release of the atomic bombs and provides firsthand information of the release “Fat man’. Since he was among the crew of people dropping the bomb on Nagasaki, his article becomes very dependable. He expresses the thrill of the crew because they had every hope that the bombing of Nagasaki would be the end of the Second World War. He then elaborates the explosion of the radioactive bomb, giving details, of the effects on the city and land. He describes the resulting crater, the flashing of the atomic light, the uprising of dust-like fire that he calls a new living thing. The article captures the attention of the reader because it has an illustration of the real damage on the ground. It paints a picture of the massive impact of atomic power. He must have written the article to narrate the experience to the United States audience. This bomb marked the end of the Second World War and a clear description of the exact bombing mission was of great interest to the American public. The article paints a picture of the atomic explosion that marked the end of the war but remains in history for its effects. Marshak, R. E., Nelson, E. C. and Schiff, L. I. “Atomic Bomb Damage-Japan and USA,”Bulletin of the Atomic Scientists, Vol. 1 (10) (1946). 6. The bulletin of atomic scientists is another valuable primary source that contains articles on the breakthroughs in atomic science. The May 1, 1946 issue elaborated the potential of the atomic bomb. Marshak, Nelson, and Schiff describe the destructive causes of the atomic bomb. The authors give details of how the blast, heat, gamma rays, and byproducts on the ground cause destruction. According to the authors, the blast causes collapse of buildings while the heat or fire can result to burns. In addition, the gamma rays cause devastating effects to the people and to objects on the ground. The Bulletin of the atomic scientists aims at updating the public on development in nuclear weapon development and this is the reason why the authors elaborate their facts in understandable terms. Cate, James, United States Air Force , Air Historical Group, United States, USAF Historical Division, Officer of Air force History. The Army Air Forces in World War II: Plans and early operations, January 1939 to August 1942, (Pennsylvania: DIANE Publishing, 1948), 1-7.