Write 6 pages thesis on the topic carcinogenesis and its prevention. These newly acquired capabilities are regulated by processes such as gene expression through chromatin structure control, damage of fatty-acid metabolism, hormonal exposure, DNA damage and alteration of cell-interactions (Reya, et al, 2001, p.507). The formation of cancer cells continues to replicate causing further mutations which finally lead to a complete neoplastic phenotype.

Write 6 pages thesis on the topic carcinogenesis and its prevention. These newly acquired capabilities are regulated by processes such as gene expression through chromatin structure control, damage of fatty-acid metabolism, hormonal exposure, DNA damage and alteration of cell-interactions (Reya, et al, 2001, p.507). The formation of cancer cells continues to replicate causing further mutations which finally lead to a complete neoplastic phenotype.

To understand this whole process let us first consider stem cells and their role in the body. According to Sell (2003, p.16), mature stem cells are present in many body tissues where they facilitate tissue development, repair as well as a replacement when necessary. All these cells have similar characteristics that enable them to replicate through a process of self-renewal as they also differentiate to form various tissues in the body. These processes are natural and occur in every normal functioning organism’s body, any alteration of the process may be the key to the development of cancerous tumors. Different theories have been put forth to explain the development of these cancerous tumors, each theory focuses on specific aspects of cancer. For instance, the theory of Cancer Stem-Cell (CSC) explains that the normal stem cell differentiation process when altered forms cells that are terminally differentiated which in turn causes mutation accumulation causing tumor (Trosko, 2004, p.211).

At the beginning of the 20th century, people had no explanations of the exact causation of cancer cells. Chang, et al, (2001, p.206) explains that the initial belief was that chemicals were among the causes of cancer with neither a particular understanding of the molecules that caused cancer nor their target cells. What was lacking at this time was knowledge of chemical mechanisms leading to cancer and the tumor progression characteristics which are brought about by molecular changes.

10 Assignment: Health Policy Briefs

Health policy briefs provide succinct overviews of health policy topics. The intended audience is policymakers, journalists, and others concerned about improving health care in the United States. The briefs explore arguments from varying perspectives of a policy proposal. They guide available research behind each perspective. Health policy briefs are created by experts in the field through funding from public and private grants.

Select one policy brief from the Robert Wood Johnson Foundation website:

Robert Wood Johnson Foundation. Health Policy in Brief. https://www.rwjf.org/en/library/collections/health-affairs-briefs.html

  1. Identify the primary issue discussed in the brief, summarize the brief, and state the relationship of the issue to APN practice
  2. List at least 3 strengths, weaknesses, advantages, and/or disadvantages of the issue
  3. Describe at least 3 solutions or recommendations for the issue
  4. In your role as an APN, list at least three ways you would advocate for or against the policy implementation?

In your paper, you may take the position either for or against the policy proposal, or both.

Page length: 3-4 pages exclusive of cover page and references.

Support your paper with a minimum of three scholarly references.

Gender Issues Surrounding Child Marriages in South Asia. The work is to be 7 pages with three to five sources, with in-text citations and a reference page.

I will pay for the following article Gender Issues Surrounding Child Marriages in South Asia. The work is to be 7 pages with three to five sources, with in-text citations and a reference page. Allowing young girls to get married earlier it stagnates their mental growth, affects their physical growth by bearing children before they have physically matured, and removes opportunities for education and work.2 In turn, these problems create gender-based issues such as economic marginalization, poor health care, high sexual health risks, encountering domestic violence through the male or his relatives, frequent abuses from males, and getting trapped in a cycle of poverty and dependence on men.34As such this marriage is prohibited by international treaties and countries due to the revocation of a basic right of free choice.5However, despite global initiatives in eradicating this practice and the passing of various treaties and bills that deems child marriage to be illegal, up to 46% of women in South Asia of the ages 20-24 reported to have been married at very young ages, with India alone having about 10 million child brides despite The 2006 Prohibition of Child Marriage Act.6With the strong influence of patriarchy in nearly all South Asian nations, it will take a lot of conscious effort by women, men, and higher authorities to gradually reduce the number of child marriages in this region, as well as in changing the traditional mindset of those who allow and continue to patronize such acts against human rights of children and especially females.

The high prevalence of child marriages in South Asia has been sanctioned by the prevailing patriarchal societies which encompass rules and legislations of states and nations, and in turn is fueled by gaps and poor enforcement of anti-child marriage laws, poverty, illiteracy, natural disaster or conflicts.7In addition, the existence of personal laws in some Muslim countries affect how laws regarding forced marriages are imposed or sanctioned, wherein laws tied with marriage, inheritance, divorce, and custody are tried differently under Sharia law, allowing the perpetuation of child marriages as the Sharia laws deem&nbsp.fit.

article review of the social order and violent disorder: an analysis of north carolina in the revolution and the civil war

I need some assistance with these assignment. article review of the social order and violent disorder: an analysis of north carolina in the revolution and the civil war Thank you in advance for the help! Article Review of The Social Order and Violent Disorder: An Analysis of North Carolina in the Revolution and the Civil War

This article goes an extra mile to explain how the two approaches recommended by Eckstein can be used to explain the complicated reasons for the violence. It explains the two approaches separately as the structural and the behavioral hypotheses. The structural hypotheses explain the general characteristics the society exhibits that can explain the reason for internal war. The behavioral hypotheses on the other hand discuses the society’s perception and studies how the social circumstances were tolerable at a particular place and time, but could not be tolerated somewhere else leading to war. The authors however do not seem to have their points well spelt out. On top of that, the thesis is stated half way into the paper while according to the standard format, the thesis should be at least somewhere at the beginning of the paper so that a reader can have a clear understanding of what the author wants to focus on. In addition, there seems to be several points of focus and not just one particular point that one can point out as the main thesis. Apart from that, the paper does not seem to have a flow as the points appear mixed up and one has to keep jumping bits on the paper in order to understand the points the authors are trying to outline. In their explanations, especially on the hypotheses stated by the quoted author, they focused on one reference, which should not be the case since the author might have a biased view.