Just need these two questions answered in brief detail. I will attach the chapters from the book.
The questions are below:
28. The federal use of taxpayer funds for assistance in economic downturns and times of crisis remains a contentious issue. List at least two (2) arguments in favor of and two (2) arguments against federal assistance cited in the text.
29. List and briefly describe the four (4) stages of the policy process outlined in the text.
Consider the following scenario:
A principal shared, “We had a threat written on a bathroom wall that said, dont come to school this day, and half of the school didnt show up based on the threats. In the wake of that, people started reporting other things on social media. Things just seemed to spiderweb off of the initial threat and we ended up with kids suspended and expelled. To see the whole process unfold has been eye opening.”
Respond to the following questions:
How would you lead the school through this situation?
What information does the superintendent and board need to know?
What should you tell the public?
How can you avoid this turning into a crisis?
1. I would lead the school with specifics, not bringing in vague details unrelated to the matter, focusing only on facts and student safety. Not exposing student discipline is also priority.
2. The superintendent and board should know details and specifics related to the information, families and students affected, and a contact or point person regarding the matter.
3. The public should know there was a threat and that it has been dealt with and determined not a danger to students per local law enforcement. They should also know a contact or point person to direct questions or concerns related to this matter and how to get a hold of them. They should also be reassured that in matters like this there are specific protocols in place to determine threats and dangers to our school community.
4. Not instilling fear in the public would be my first step in responding to this situation. First local authorities would need to be contacted to determine if there is an actual threat to the safety of the school. Next a statement that does not provide specifics on the threat, just that there is a threat, and that it has been dealt with accordingly by school administration. ensuring families that students are safe and if we thought otherwise they would be informed and removed from any hostile environment efficiently.
THIS IS A UNDERGRAD LEVEL ESSAY!!! do not focus on what receptors are but on the specific GCPRS mediating the effects of neuropeoptides. and must provide experimental evidence from the papers listed below.
Large, highly complex networks of regulatory proteins control signaling, desensitization,
internalization and recycling of G protein-coupled receptors (GPCRs). These regulatory
interactions appear to be particularly important in mediating the effects of neuropeptides.
However, several lines of evidence indicate that interactions between the receptor proteins themselves may also play a major role in these processes.
Please provide an overview and critical evaluation of the experimental evidence supporting a role for receptor-oligomers, both homoand heteromeric, in the regulation of signaling and intracellular trafficking of GPCRs. Place a strong focus on GPCRs mediating the effects of neuropeoptides. Please use the review articles suggested below as starting points for your own literature research. Please also suggest an experiment that would be helpful in supporting your conclusions.
Suggested reading:
Ulloa-Aguirre and Conn (2009) Targeting of G protein-coupled receptors to the plasma
membrane in health and disease. Front Biosci 14: 973 – 994.
Farran B (2017) An update on the physiological and therapeutic relevance of GPCR oligomers.Pharmacol Res 117: 303-327.
Chini B (2019) Expanding neuropeptide signaling by multiplying receptor functional states and sub-cellular locations. Cell Tissue Res 375: 49-56.
-Why is this topic or question important?
-What is already known about this topic?
-How do we know this? (i.e. what were the important experiments that gave us this information?)
-What are the outstanding question(s) concerning this topic? (i.e. what do we not know?)
-How will we go about answering these questions? i.e. Propose at least one experimental approach to address this/these questions.
Abstract: Define the topic, how is it important. What is known and what is your question.
-Introduction: Written after you have assembled the narrative/figures, and chosen how to tell the story. Need to tell the reader WHY this topic is important, and what they need to know to position the new findings within the field.
-The Question: Explain where the holes are. Why dont we know this, is it a technical limitation?
-Hypothesis: Given what you have learned about cell biology, how do you think it might work? There are always a few options, discuss them a bit. This is where a figure/model helps. -Experimental Approach: What will you do? Assume you have all the money in the world.
-Interpretations, conclusion, impact: How will you draw a conclusion from your experiments, what will it mean in the bigger picture?
-References: Use a reference manager software like Endnote to format the citations.
Instructions: Discuss and describe key trends affecting pharmacy administration toward achieving operational excellence. What affect does these trends have on the pharmaceutical supply chain?
Requirements: Complete assignment using APA format-title page, references and in-text citations. Submit the assignment in Blackboard as a Word document.
Length requirement: minimum 500 words. This does not include the title page and reference list.
Page 1 title page, page 2 and 3 500 words, page 4 reference page
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