Pamphlet addressing non-scientific community and presentationAddresses Learning Outcome: Recognize risk factors leading to disease and identify preventive measures and treatments.This assignment is designed for you to demonstrate your ability to communicate your knowledge of a disease to the lay (non-scientific and non-medical) public.The disease or disorder should not be a common disease that has already addressed in our course.  Common diseases include coronary artery disease, Alzheimer disease, arthritis, diabetes, AIDS, hypo- and hyper-thyroidism, hypertension, psoriasis, sleep apnea, Lyme’s Disease, sinusitis, allergic rhinitis, mononucleosis, asthma, urinary tract infections, many STDs (check with your instructor), irritable bowel disease, strep throat, MRSA, polio, tuberculosis, Lockjaw, anorexia nervosa, autism, Down syndrome, and many cancers (check with your instructor).  For any additions to this list, check with your instructor.In this assignment, you will develop good working knowledge of unique (uncommon) chronic disease or a unique preventable disease.    Check with your instructor for approval of your topic selection.Process You will choose a unique chronic or preventable disease during the first two weeks of the course. Seek approval for your topic from your instructor. Create an informative pamphlet about the chosen chronic or preventable disease for a non-scientific community. Ideally, the pamphlet should be in the form of a six-page pamphlet.Content The pamphlet should contain the following: Content and language that targets a lay audience.  All terms should be explained and diagrams and graphics should be provided to clarify concepts and ideas. A brief description of the disease, including its symptoms and signs Explanation of the effects of the disease on healthy body function including cellular, tissue, organ and organ system levels Risk factors contributing to the onset of the disease Description of preventive steps to avoid the disease (if avoidable) Available diagnostic and therapeutic tools Outcomes of the disease (such as prognosis or recovery potential) Information about how a person suffering from the disease can maintain a desirable quality of life, minimize or slow the progress of the diseaseFormat of the pamhlet Single-spaced Tri-fold All content written in your own words Reference citations included in APA format (not part of the tri-fold; should be provided on a separate page)Grading RubricThis project has three phases: 1. Select a Topic.  By the end of the second week of the course (see Course Schedule for due date), you will be required to post your chosen topic and information about why you chose it in a designated area in the Conferences.  The information you present should include sufficient detail to demonstrate that you have completed some preliminary research and should present a clear rationale for your choice.2. Develop a reference list and outline.  By the end of the fifth week of the course (see Course Schedule for due date), you will be required to submit a list of references and an outline for your pamphlet in the Conferences.  The outline should go beyond the list of required elements to sketch out some of the facts you have learned about the disease – for example, it might include a bullet list of the symptoms.  The reference list and outline should demonstrate that you have conducted at least preliminary research into the topic and that you have a grasp of the facts related to the disease.  Note that the reference list and outline that you present in week five could still be subject to change as you complete the research and writing of your final paper.3. Write the pamphlet and be prepared to discuss it.  You will post the pamphlet in a designated discussion conference by the end of week 7 (see Course Schedule for exact due date). As a presenter and topic expert, you will be responsible for answering classmates’ questions and reacting to their comments. You will also read classmates’ pamphlets and will have a chance to discuss them during the last week of the class.At a minimum, your pamphlet should contain the following required elements: Introductory paragraph describing your subject and its importance Body of the pamphlet Addresses signs, symptoms Explains effects of the disease on healthy body functions, and relates this to signs and symptoms Analyzes risk factors and preventive steps Describes maintenance of quality of life Discusses diagnostic and therapeutic tools Explains expected outcomes and prognosis Describes current areas of research into prevention, treatment or cure Describes possible future areas of research into prevention, treatment or cure References Conclusion – summary of your findingsList all references at the end of your pamphlet. You must use at least five references from credible, scientifically rigorous sources and cite them using American Psychological Association (APA) style. Two or more references should be from the UMUC Library. The references cited should be no older than seven years (published 2004 – 2011).  References should be listed on a separate page that does not count toward the required length of the paper.Pamphlet (final product) is worth 12% (class 7) Introduction Addresses signs, symptom Explains effects of the disease on healthy body functions, and relates this to signs and symptoms Explains effects of the disease on healthy body functions, and relates this to signs and symptoms Analyzes risk factors and preventive steps Describes maintenance of quality of life Explains outcomes and prognosis Describes current areas of research into prevention, treatment or cure Describes possible future areas of research into prevention, treatment or cure Conclusion Final list of references included in pamphlet Clarity, proper grammar, punctuation, spelling

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My pathogen is Chaga’s diseaseHow to create a case studyThe case studies are meant to be an enjoyable, interesting, and informative assignment.  This is your chance to show that you understand the key teaching points about a microbe and to communicate these points to in a written format.  Have at least 3-4 key referenced points in each of the five areas.  The chart below suggests the type of information requested for the pathogen. Outlines can be in whatever form you prefer (bullets/charts/outlines/diagrams or a mix).  Be sure to include two discussion questions (and provide complete answers) that you can incorporate into your case study (place them at the end of your write-up). These questions should help connect your case to other material in the course.  For example, what other microbes have an A-B toxin?  What other viruses are transmitted by fecal-oral spread?  Pertinent references can be listed at the bottom of your outline in a small font. Use Council of Science Editors (CSE) Style format for all references. Your textbook may be listed as “Microbiology:  A Human Perspective Eugene W. Nester et.al. McGraw-Hill Publisher 7th edition/ 2012”.Typical CaseWhat does a typical case look like?  Use the standard format for a patient presentation with chief complaint (CC), history of present illness (HPI), key physical exam details (PE), lab findings, signature signs, and any other important findings.Description of the infectious agentIf it is a bacterium, how is it classified?  If it is a virus, what kind of nucleic acid does it have?  Does it target specific cellular types (tropism)? Does it form a spore? Is it aerobic? Is it intracellular?  Can it only be grown in a specific type of media? How is it distinguished from other members of the species? Does the pathogen have a significant history with humans or animals?EpidemiologyWhat do you feel are the most important points about the epidemiology of the disease?  Incidence? Portal of entry? Source? Is it a normal microbiota component in the human body? Does it only occur in certain populations or certain geographical areas?  Is there a vector involved? What and who is the vector? Is it zoonotic? Does it appear seasonally? Are there currently any outbreaks of this pathogen? What is its ecological niche? Is there a reservoir? Are there currently any outbreaks or epidemics of disease from this pathogen?PathogenesisWhat is the range of diseases caused by the agent?  What organs are affected? What symptoms might the patient have? What is the disease course?  Will the patient recover? Are there any long-term sequelae of infection? Latency?Prophylaxis/TreatmentIs there an antitoxin? Specific antibiotics or a class of antibiotics that are used? Is there a vaccine available? Is treatment curative? Does infection make you immune? Is this immunity life-long? Is there drug resistance? Are there novel treatments?Addenda The written case presentations are submitted through Blackboard in Unit 5 of the course. When you reach Unit 5, be sure to e-mail your instructor to receive a list of the Case Study selections. Please name the files in the following manner “Lastname Firstinitial CS Y”.  For example, if I am submitting a Case Study on tularemia, I would name the case study file “Frisardi M CS tularemia”.  For the Case Study, you are asked to provide at least the information requested in the boxes. The boxed questions are suggestions for the minimum amount of information within each category. The more detailed the information, the better the study. You may consult your textbook, CDC, Google Scholar, NCBI, WebMD, etc. to find the information. For example, if you perform a Google search using the name of the pathogen and the word ‘vaccine’, you will find information on current vaccines (if any), those in clinical trials, vaccines used only in animals, etc. Be sure to provide two (2) discussion questions (as well as provide answers) with your case study.Be sure to consider the directions carefully and include all the requested information (especially the two discussion questions with responses and scientific literature references). Discussion questions you may choose from, choose 2: 1.After receiving personalized genomic information, how might you use such knowledge with respect to your own health? 2.Would a genetically tested family member providing children or other family members with information regarding genetic information (such as carrier status) be desirable? 3.Might such testing be used as a prerequisite for employment, spousal selection, marriage, adoption, or IVF embryo implantation? 4.What was the specific original intent of the intervention or procedure described in each of the papers and what was their unintended consequence(s)? 5.Can you offer a solution or remediation for any or all of the resulting consequences from these interventions? 6.What is the Hygiene Hypothesis (described in the Roduit paper) and how is it related to this discussion?

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