Discuss the pathophysiology of diabetes mellitus and comment on the statement that eating too much sugar causes diabetes.



Matt is a 21 year old male who is 6’1” tall and weighs 250 pounds. Maria is a 19 year old female who is 5’8” and weighs 140 pounds. Matt has a family history of diabetes mellitus. Matt and Maria are close friends and do most things together.  On this given day, they were heading out very early in the morning to eat breakfast so that they could get to UCF for their classes before the parking lots filled up. On their way, they stopped at IHOP for breakfast and Matt had the Chicken & Waffles for breakfast, Banana Crepes with Nutella, and one cup of coffee.  Maria had BaconTemptation Omelette, a side of Buttered toast, and a 16 oz. of Tropicana Premium Orange Juice. 
After their morning classes they met up again for lunch. This time they went to Burger King for a quick bite before heading back to an afternoon in the library. For lunch, Matt had the Whopper w/ cheese, a Dr. Pepper (medium) and a side order of the 9 piece Chicken Nuggets. Maria had the Bacon and cheese crispy chicken sandwich w/o mayo, and a side order of large French fries, and a Coke (large).
They studied until late into the afternoon. On the way home they decided they did not have time to cook, so they stopped at Subway to pick up dinner. At Subway Matt had 12″ Sweet Onion Chicken Teriyaki, a bag of Lay’s classic chips and a Coca Cola (21 oz. with no ice). Maria selected the 6″ Chicken & Bacon Ranch Melt, a Chocolate Chip Cookie and yet again, a Sprite (21 oz. with no ice)
Well into the evening’s feature movie on TV, they both decided that a pizza would be just the right thing to have to finish off the evening. They ordered a 12 ‘’ Medium Pan Pizza: Meat Lover’s Pizza from Pizza Hut. They each had three slices along with a glass of water (they wanted to save the remaining slices for lunch the following day).
The movie ended and they drifted off to bed to rest up to face yet another day tomorrow as UCF students.
This is a typical day for Matt and Maria. Other than their usual study, eat and sleep routine, they do manage to get to the gym about 3 days a week. At the gym they usually manage to get in a good 2.5 miles run at an average of 4.26 mph on the treadmill during each visit.
Assignment 1:
Your responsibility for this report is to:

Determine if Matt and Maria are about the correct weight based on their height. To do this, you can compare their BMI to published medical tables related to ideal values.
Evaluate their diet to determine how many calories they both managed to consumed on this particular day. (Keep track of where you find the information, for we will revisit this data later in the semester for a more detailed analysis). 
Being that this is a typical routine for Matt and Maria, would you expect them to be heavier or lighterat the end of one year and by about how many pounds? You might need to consider their Basal Metabolic Rate (BMR) in determining the total caloric expenditure.
Would Matt’s eating lifestyle affect his chance of having diabetes mellitus?
Discuss the pathophysiology of diabetes mellitus and comment on the statement that eating too much sugar causes diabetes.  



Concisely summarize the H&P findings as if you were presenting it to your preceptor using the pertinent facts from the case.



Guide to NR511 Case Studies

Part
1
In
Part 1, you are given a patient scenario.
Using the information given, answer the following questions:

1.
Briefly
and concisely summarize the H&P findings as if you were presenting it to your preceptor using the pertinent
facts from the case. Use shorthand where
possible and approved medical abbreviations.
Avoid redundancy and irrelevant information.

Example:

J.S.
is a 34yo male with a CC of acute onset ST x 3 days [provide additional
information from the history that is relevant].

Physical
exam is significant for [provide relevant physical exam findings].

*Do
not simply rewrite the information as it is presented in the case report. This
should mimic how you would present this patient to your preceptor.

2.
Provide
a differential diagnosis (plural) which might explain the patients chief
complaintalong
with a brief statement of pathophysiology for each.

Example:

Diagnosis
#1
-Pathophysiology
statement

Diagnosis
#2
-Pathophysiology
statement

Diagnosis
#3
-Pathophysiology
statement

3.
Analyze
the differential by
using the pertinent findings from the history and physical to argue for or
against a diagnosis. Rank the
differential in order of most likely to least likely.(This
is where you present your argument for EACH DIAGNOSIS in your differential
using the patients subjective and objective information that was given).

Example:

Diagnosis
# 1, 2, & 3 (provide an analysis for each of the diagnoses listed above)
A
brief argumentas to why this condition should be considered plus:
-Pertinent
positive symptoms which support the diagnosis
-Pertinent
negative symptoms which support the diagnosis

4.
Identify any additional tests and/or
procedures that you feel is necessary or needed to
help you narrow your differential. All
testing decisions must be supported with an EBM argument as to why it is
necessary or pertinent in this case. If
no testing is indicated or needed, you must also support this decision with EBM
evidence.(This
is where you identify, based on what you know thus far, test or test(s) that
you would perform TODAY which would help you narrow your differential diagnosis).

*Do not list all of the
possible tests that can be done. You are being evaluated on your diagnostic
reasoning skills as well your ability to make decisions that are in-line with
current practice recommendations. Just because a test is available does not
mean it needs to be done.

Example:

Lets
say my differential included bronchitis and pneumonia. In this case, a CXR might be useful in
differentiating the 2 conditions.
However, remember that you have to have an EBM argument for this
decision. So make sure you are
telling the reader why this is the best choice based on the literature (i.e.,
it is not enough to say the test and cite the author & date). In this instance, my argument might look like
this: According to the Infectious
Disease Society of America (2012) a CXR is considered the gold standard for
diagnosing pneumonia. Keep in mind that
you also need an EBM argument if you decide NOT to test too.

Part
2
In
Part 2 you might be given some additional history, exam or test findings. Using this information and the
information in Part 1, answer the following questions:

1.
What
is your primary diagnosis for this patient? Tell the reader how you came to this
conclusion using the information that you were given (i.e., CXR result, lab
result). Interpret the results into your
diagnosis decision (i.e., tell how this information helped you to narrow your
differential to the one diagnosis that you chose).

Example:

Diagnosis:
Pharyngitis, streptococcal

Rationale:
The CBC results are
normal which rules out infection and anemia. The RSA test was + which tells me
that she has a very strong likelihood of streptococcal pharyngitis.

In the case where a diagnosis was made
based on clinical presentation and history, explain the criteria with an EBM argument
to support.

2.
Identify
the corresponding ICD-10 Code for the diagnosis.

Example:

J02.0

You
can find a link to an ICD-10 code finder by going to the Library
homepage>Browse guides>Course directory tab>select NR511 from the drop
down box>select Go. Otherwise, a google search will provide you with several
free options you can use.

3.
Provide
a treatment plan
for this patients primary diagnosis which includes:

a) Medication-all
prescriptions and OTC medications should be written in RX format with an EBM to
support:
Medication Name & Medication Strength
Dispensing quantity:
Sig:
RF:

b) Any
additional testing necessary for this particular diagnosis-typically
done when you need more information to confirm a diagnosis or differentiate the
diagnosis. Do not state all of the
possibilities that are available. To assess your diagnostic reasoning skill,
you will need to be decisive.

c) Patient
education-self explanatory

d) Referral-self
explanatory

e) F/U plan-include if and when the
patient should follow-up

*If part of the plan
does not warrant an action, you must explain why. ALL medication and testing decisions
(or decisions not to treat with medication or additional testing) MUST be
supported with an EBM argument as you did in Part 1.

Example:

a. Penicillin
VK 500mg, Disp #20, Sig: 1 tab twice daily x 10days; RF: 0 (full RX required)

Rationale: Penicillin is
the 1st line treatment recommendation for Group A Beta-hemolytic
streptococcal pharyngitis, based on their narrow spectrum of activity,
infrequency of adverse reactions, and modest cost. (Shulman, Bisno, Clegg, Gerber, Kaplan, Lee,
Martin, & Van Beneden, 2012). My
patient has no noted allergies, so PCN VK is appropriate.

b.
No additional testing will be performed
today.

Rationale: Point of care, rapid
strep antigen tests are highly specific (approximately 95%) when compared with
throat cultures, so false-positive test results are highly unusual. Consequently, a therapeutic decision can be
confidently made based on the positive result which was reported for this
patient in the scenario (Shulman, Bisno, Clegg, Gerber, Kaplan, Lee, Martin,
& Van Beneden, 2012).

c.
Patient instructions:
-take
all medication as prescribed (Reference, date)
-F/U
in 10-14 days if symptoms are not resolved or sooner if they become worse,
etc., (Reference, date)
-Etc..

4.
Provide
an active problem list
for this patient based on the information given in the case. This is where you list all of the known
medical problems of the patient. This is
different than a differential.

Example:

1. Streptococcal
Pharyngitis
2. Hypertension
3. Obesity

List
your references that were cited above according to APA rules. Format is not
graded (Canvas does a poor job in formatting the tabs and spaces) BUT all other
APA elements are required.

References
Shulman,
S., Bisno, A., Clegg, H., Gerber, M., Kaplan, E., Lee, G., Martin, J., &
Van Beneden, C. (2012). Clinical
Practice Guideline for the Diagnosis and Management of Group A Streptococcal
Pharyngitis: A 2012 Update by Infectious
Diseases Society of America. Clinical Infectious Disease, 55(10), e89. DOI: 10.1093/cid/cis629

Guide to NR511 Case StudiesPart
1In
Part 1, you are given a patient scenario.
Using the information given, answer the following questions:1.
Briefly
and concisely summarize the H&P findings as if you were presenting it to your preceptor using the pertinent
facts from the case. Use shorthand where
possible and approved medical abbreviations.
Avoid redundancy and irrelevant information.Example:
J.S.
is a 34yo male with a CC of acute onset ST x 3 days [provide additional
information from the history that is relevant].
Physical
exam is significant for [provide relevant physical exam findings].*Do
not simply rewrite the information as it is presented in the case report. This
should mimic how you would present this patient to your preceptor. 2.
Provide
a differential diagnosis (plural) which might explain the patients chief
complaintalong
with a brief statement of pathophysiology for each. Example:Diagnosis
#1-Pathophysiology
statementDiagnosis
#2-Pathophysiology
statementDiagnosis
#3-Pathophysiology



Explain any difference between what you expected to achieve with Decision #1 and the results of the decision. Why were they different?



Decision #1

Which decision did you select?
Why did you select this decision? Support your response with evidence and references to the Learning Resources.
What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources.
Explain any difference between what you expected to achieve with Decision #1 and the results of the decision. Why were they different?

Decision #2

Why did you select this decision? Support your response with evidence and references to the Learning Resources.
What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources.
Explain any difference between what you expected to achieve with Decision #2 and the results of the decision. Why were they different?

Decision #3

Why did you select this decision? Support your response with evidence and references to the Learning Resources.
What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources.
Explain any difference between what you expected to achieve with Decision #3 and the results of the decision. Why were they different?
 you can use my sample/ edit or do a new assignment. 



Analyze ethical and legal implications related to prescribing bipolar therapy to clients across the lifespan .



Bipolar disorder is a unique disorder that causes shifts in mood and energy, which results in depression and mania for clients. Proper diagnosis of this disorder is often a challenge for two reasons: 1) clients often present as depressive or manic, but may have both; and 2) many symptoms of bipolar disorder are similar to other disorders. Misdiagnosis is common, making it essential for you to have a deep understanding of the disorder’s pathophysiology. For this Assignment, as you examine the client case study in this week’s Learning Resources, consider how you might assess and treat clients presenting with bipolar disorder.
Learning Objectives
Students will:

Assess client factors and history to develop personalized plans of bipolar therapy for clients
Analyze factors that influence pharmacokinetic and pharmacodynamic processes in clients requiring bipolar therapy
Evaluate efficacy of treatment plans
Analyze ethical and legal implications related to prescribing bipolar therapy to clients across the lifespan ..

 
The Assignment
Examine Case Study: An Asian American Woman With Bipolar Disorder. You will be asked to make three decisions concerning the medication to prescribe to this client. Be sure to consider factors that might impact the client’s pharmacokinetic and pharmacodynamic processes.
At each decision point stop to complete the following: